Laxogenin: Benefits & Side Effects Explained


A summary of Laxogenin

Do you think you’ve tried everything to increase muscle and strength? You probably hit your lifts hard, consume sufficient protein, sleep soundly, and yet, you can’t seem to get that 1% edge that will get you over the top and get you to the big boys’ club.

It is also possible that you’ve heard of every supplement currently in the market.

Apart from full-blown steroids, you’re probably familiar with Creatine, pre-workout, BCAA’s, whey protein and the rest. However, have you heard about one supplement that is literally one step away from steroids?

Enter Laxogenin. If you want, call it the 1% booster. This is probably what your regiment has been missing. Before you dismiss it as hype, how about you learn a thing or two about this wonder substance.

The article below covers all you’d like to know about Laxogenin. Whether it is a steroid or not, its benefits, dosages, and side effects as well. Eventually, you’ll be able to decide whether it’s something you want to include in your regimen.

Let’s get to it!

What is Laxogenin?

For starters, scientists refer to this substance as 5α-Hydroxy-Laxogenin. It is an anabolic building block that aids your body to produce its anabolic compounds. What’s more, it is derived from plants. In particular, it is a naturally occurring steroidal sapogenin that acts as a genesis for semi synthesis of steroid hormones. 

Laxogenin is extracted from a specific plant, smilax sieboldin, a close relative of asparagus. It belongs to a group of plant-based steroids known as brassinosteroids (Mustard also belongs to this group). Scientists believe that Laxogenin is partly responsible for the growth within the plants.

Essentially, what this means is that Laxogenin is a plant-based anabolic compound that helps build bigger molecules from smaller molecules. In simpler terms, this compound had to grow after working out. That is, at the gym, you break down your muscle (catabolism), during recovery, your muscles become more prominent (anabolism) to prepare for the heavier weights.

Therefore, it suffices to say that Laxogenin is a natural steroid found in a category of plants known as brassinosteroids. However, you’d like to know that most of the supplements usually contain its synthetic derivative, 5α-Hydroxy-Laxogenin.

However, unlike typical muscle builders, you know, this is not a prohormone or an anabolic steroid per se. This means that it will not be converted to other powerful hormones such as testosterone and dihydrotestosterone, and nor does it run the risk of increasing estrogen.

Therefore, you do not expect this natural steroid to cause effects such as:

  • Liver and kidney damage (hepatotoxicity)
  • Testing positive for steroids in anti-doping tests
  • Testosterone suppression or sex hormone imbalance
  • Need for PCT (post-cycle therapy) to restore testosterone production

Human steroid hormones such as testosterone function by influencing the nuclear receptors. On the other hand, plant steroids such as this one act through a completely different pathway. They attach the cell surface, which then sets off a signal to enhance muscle building to the inside of the cell. Notably, plant steroids activate a protein known as AKT1 or protein kinase B that promotes muscle building and prevents muscle protein breakdown.

Buy Laxogenin from the #1 USA Supplier

Besides, the derivatives of organic Laxogenin block the enzymes known for breaking down cAMP (phosphodiesterase). Subsequently, it increases cAMP levels and ultimately enhances the fat breakdown and activates the sympathetic response (fight or flight).

Overall, Laxogenin is a muscle toning supplement for athletes and bodybuilders and is claimed to increase protein synthesis in muscles by up to 200%.

Here is a more in-depth look at how Laxogenin can help you in your muscle-building endeavors.

Laxogenin Benefits

The chances are that you’ve probably heard the term safe alternative to prohormones or steroids. However, if you observe, the term was perhaps misused. If you consider all the types of muscle building supplements you know, then disregard the ones that impact hormone levels, you will be left with a very short list of substances that can help to improve your performance, and recover faster. Similarly, it complements the use of protein supplements.

You will also be pleased to know that Laxogenin can be stacked with other supplements such as estrogen blockers and testosterone boosters to boost muscle building and recovery across two distinct pathways. This is more sensible than stacking two or more testosterone boosters with similar mechanisms of action.

Interestingly, Laxogenin can be used for post cycle therapy. After a prohormone or steroid cycle, you can use this substance as it supports anabolism through a different mechanism compared to testosterone boosters.

Other benefits of Laxogenin include.

  • Directly increases protein synthesis (anabolism) and reduces protein breakdown (anabolism)
  • Features adaptogenic properties (promote homeostasis, decreases cellular sensitivity to stress, and stabilizes physiological processes)
  • Increases strength
  • Encourages the development of lean mass
  • Enhances thyroid function
  • Regulates blood levels
  • Suppresses cortisol levels
  • Promotes optimum cholesterol levels
  • Contributes to fat loss during cutting

Another excellent feature of Laxogenin is that it is fast-acting, which means that you will receive the benefits outlined above quickly and effectively.

Laxogenin Dosage

The recommended dosage for Laxogenin has been a topic of considerable debate in the fitness community. Reasonably so, the optimal dosage for maximum benefits may vary with each individual.

For instance, the dosage used during the substance’s clinical trials is 100 milligrams. However, should this be used as the universal dosage? Probably not, because one’s ideal dosage highly depends on different factors such as body weight and how advanced one is when it comes to bodybuilding.

The best way to find the dose that works for you is to use a trial and error approach.

Typically, Laxogenin is sold in 25-milligram pills, and the recommendations vary from three to six times daily. This means that you should take somewhere between 75 to 150 mg. With this in mind, you should begin at the bottom of this spectrum and only increase the dosage if you feel like you are not getting the full range of benefits.

While it doesn’t really matter when you take your serving of Laxogenin, it is best when you take it with meals as it increases its rate of absorption into the system.

Once you’ve decided your ideal dosage, you should run it for approximately eight weeks. Well, you can run it for longer without encountering any side effects. However, it is recommended that you cycle the substance on and off to prevent your body from getting used to it.

Laxogenin for Bulking, Cutting, and Recomping

Holistically, Laxogenin is used to enhance muscle growth affinity one also reducing stress. That being said, this substance will do two things; it will build muscle and burn fat stores. As a result, this substance is ideal for the full spectrum of activities, including bulking cutting and even doing both simultaneously (recomping).

Up to the extent of our research, we found that Laxogenin is a very stackable and dynamic supplement. One of the top stocks with tried Laxogenin with a testosterone booster and epicatechin. Apart from pills, this substance can also be paired with typical workout supplements such as Creatine, fat burners, and pre-workouts, among others.

Is Laxogenin Safe?

Pretty much, yes. What makes this natural steroid so special is that it has only one side effect; headache.

Yes. The worst-case scenario when you use Laxogenin is experiencing a slight headache, and this mostly occurs when the substance is taken in high doses (above 150mg).

Undoubtedly, the primary reason why this substance has gotten so much popularity is that it can help you gain some substantial muscle without side effects.

Unlike prohormones and anabolic steroids, this substance will not interfere with your natural hormone levels. This makes it perfect for use by both females and males alike.

The cherry on the pie is that it does not affect your endocrine system.

As a matter of fact, Laxogenin creates homeostasis (a state of equilibrium) within the body. Consequently, it can also reverse the adverse effects caused by prohormones.

Purchasing Laxogenin

Laxogenin is usually sold in capsules. Other forms include topical creams and liquid emulsions.

Several muscle building supplements have Laxogenin as one of their active ingredients, not to mention a handful of them that have it as the primary ingredient. 

Some of the most popular Laxogenin supplements include

  • Halo (Redcon1)
  • Progenin
  • Primavar (Primeval Labs)
  • Nano Genin (Assault Nano Series)
  • Anafuse (Vital Labs)
  • STR3GTH (Olympus Labs)
  • Ano-Genin (Blackstone Labs)
  • Secreta Bridge (LGI)

You can purchase Laxogenin on Amazon or iHerb, among other stores.


Before we give the final word on Laxogenin, what did you make of it? Is it worth a try? Let’s recap some crucial takeaways about this substance. Laxogenin is a plant-based steroid. Unlike other steroids and prohormones, it does not affect one’s natural hormone production.

This compound boosts muscle growth and contributes to fat burning without side effects, unlike most of its counterparts in the same category. Research findings indicate that Laxogenin may stimulate muscle growth, physical fitness, and muscle recovery. It might also help to reduce blood sugar and combat muscle wasting diseases.

The majority of the Laxogenin users praise it for decent muscle gains and its safety. However, some complain about headaches at higher doses.

Buy Laxogenin from the #1 USA Supplier